Wedad Al-Qahtani

King Saud University & Naif Arab University for Security Sciences - Main researcher & first author of this study

She is the first scientist who designed 4 specific signature peptides by developing a mass spectrometric approach to quantify Lamin A/C transcript variants. To date, there have not been specific antibodies for the individual Lamin A/C transcript variants. Her developed method is reproducible, reliable, and sensitive for measuring different Lamin A/C transcript variants in different cell lines. The developed method of chromatogram has a well-resolved peak of Lamin A/C
transcript variant proteins without interference and could be easily applied in studies of all human laminopathies (up 300 disease).